7D QSAR Based Grid Maps Generated using Quantum Mechanic Probes to Identify Hotspots and Predict Activity of Mutated Enzymes for Enzyme Engineering

June 15, 2020by admin

7D Grid Technology uses Quantum Mechanic probes to “capture information across the enzymatic reaction and across the enzyme-substrate system”. This information is used by AI methods, Convolutional Neural Networks, and Support Vector Machines, to design enzymes and derive focused libraries. Based on the projects done in the last 2.5 years, we can say that promiscuous activity to pilot scale biotransformation can be achieved with a focused library of 30-100 enzyme variants generated using 7D Grid Technology. (Under Preparation)