A plant-derived composition of active ingredients of certain plant extracts is provided to treat the affections of the Human Upper and Lower Respiratory Tract. The invention applies to healing and curative effects of certain active ingredients in the extracts of plants such as Wilbrandia ebracteate, Plumbago zeylanica, Azadirachta indica, Juglans nigra, Eucalyptus globulus, Mentha piperita, Curcuma longa, Moringa oleifera, Lawsonia inermis, flower extract of Lawsonia inermis and extract of coffee beans to treat affections of the human upper and lower respiratory. (Patent No: 202041046829)