Kcat Enzymatic brings Enzyme Engineering & Biocatalysis Revolution by using upfront in-silico in-house developed methods and algorithms using 7D Grid Technology for enzyme engineering.
7D Grid Technology uses Quantum Mechanic probes to “capture information across the enzymatic reaction and across the enzyme substrate system”. This information is used by AI methods, Convolutional Neural Networks, Support Vector Machines, to predict kinetic properties of the enzyme.
The method is highly efficient to differentiate enzymes with high activity and enzymes with low activity, a precursor for making focused enzyme libraries.
This technology is used as a partial de-novo designer which shows promising results in our projects to predict substitutions and come up with enzyme variants that show promiscuous activity (gram scale) to kilogram scale substrate conversion.