About us
Interactively procrastinate high-payoff content without backward-compatible data. Quickly cultivate optimal processes and tactical architectures. Completely iterate covalent strategic theme areas via accurate e-markets.
WHAT WE DO
Choose our technology for better tomorrow
KCAT ENZYMATIC is an enzyme/protein engineering group that specializes in providing optimized enzymes for industrial applications.
Our mission is to develop tools and technologies using Quantum Mechanics and Artificial Intelligence to delineate structure-function relationships of enzymes.
HOW WE DO
END TO END PROTEIN OPTIMISATION SOLUTION
Kcat Enzymatic is an enzyme/protein engineering group that specializes in providing optimised enzymes for your applications. We explore the transition and intermediate states of biocatalytic reactions and capture transient events of a reaction at the atomic and electronic level. We implement our internally developed algorithms to examine and derive focused libraries of enzymes with desired properties.
ENZYMATIC DECODING ®
Using our proprietary method ENZYMATIC DECODING ®, we discover new biocatalytic routes for chemistries using Active Site Repurposing Technology. We have developed an in-house database that contains ~35000 enzyme structures integrated into quantum chemical grids. The objective is to find non-infringing enzymes for existing biocatalytic reactions and identify new enzymatic routes for tough chemical reactions.
INDUSTRIAL SCALE-UP
Our end products are enzyme samples that are tailored to match a specific cost
window. This must be tested at the Scale-up industrial bioprocess production level; it
starts from enzyme engineering, and organism engineering to large-scale process optimization. What was at the lab-scale production previously (gram level production) has been upgraded to kilogram scale level production using both engineered enzymes and organisms.
window. This must be tested at the Scale-up industrial bioprocess production level; it
starts from enzyme engineering, and organism engineering to large-scale process optimization. What was at the lab-scale production previously (gram level production) has been upgraded to kilogram scale level production using both engineered enzymes and organisms.
Our Team
KCAT- COMPUTATIONAL LAB
Our computational lab situated in Queens Road, Bangalore, houses A100, A6000, HPCs, RTX Work stations, Summing up to 62000 CUDA cores
Algorithms implementing Newtonian law of motion and Schrodinger’s equation combined with artificial intelligence are our favourites. In this process, we build both hardware and algorithms which synchronize to scale up the molecular-level understanding of enzymatic reactions.
Our team develops algorithms to study the mysterious nature of enzymes, mechanistic details of reactions, and atomistic and energetic details of chemical reactions fitted inside an enzyme; to engineer industrially viable biocatalysts.
For example, let us jot down some of the challenges in this field like the impact of higher substrate concentration, temperature, and varying pH on the enzymes in a bioreactor. All of the above are rate-limiting factors in whole-cell biocatalysis and can be solved using computational methods.
KCAT- COMPUTATIONAL LAB
Our computational lab situated in Queens Road, Bangalore, houses A100, A6000, HPCs, RTX Work stations, Summing up to 62000 CUDA cores
Algorithms implementing Newtonian law of motion and Schrodinger’s equation combined with artificial intelligence are our favourites. In this process, we build both hardware and algorithms which synchronize to scale up the molecular-level understanding of enzymatic reactions.
Our team develops algorithms to study the mysterious nature of enzymes, mechanistic details of reactions, and atomistic and energetic details of chemical reactions fitted inside an enzyme; to engineer industrially viable biocatalysts.
For example, let us jot down some of the challenges in this field like the impact of higher substrate concentration, temperature, and varying pH on the enzymes in a bioreactor. All of the above are rate-limiting factors in whole-cell biocatalysis and can be solved using computational methods.
KCAT- BIOTECHNOLOGY LAB
Our Biotech Lab is situated in Bangalore Bioinnovation Centre (BBC), Electronic City, Bangalore. A formidable team with 36 years of cumulative experience in cloning and protein expression. The lab has the technical capabilities, manufacturing capacities, and geographical reach to excel and grow
The lab facility can execute high throughput screening of enzyme variants and develop enzyme assays for scale-up biocatalysis.
At present, we can produce enzymes and test up to 30 g/L of substrate conversion. We are also developing a faster method for engineering enzymes integrated with cutting-edge technology CRISPR-Cas9.
Amwerk is the answer
Look no further
Our team
We’re passionate about serving our clients to the fullest, while continuously growing, learning, and innovating. With competencies across multiple industries, we offer our customers a more reliable supply chain and confidence in the long life of their program.
Bring to the table win-win survival strategies to ensure proactive domination. At the end of the day, going forward, a new normal that has evolved from generation X is on the runway heading towards a streamlined cloud solution. User generated content in real-time will have multiple touchpoints for offshoring.
Capitalize on low hanging fruit to identify a ballpark value added activity to beta test. Override the digital divide with additional clickthroughs from DevOps. Nanotechnology immersion along the information highway loop .
Podcasting operational change management inside of workflows to establish a framework. Taking seamless key performance indicators offline to maximise the long tail. Keeping your eye on the ball while performing a deep dive on the start-up mentality to derive convergence on cross-platform integration.
Collaboratively administrate empowered markets via plug-and-play networks. Dynamically procrastinate B2C users after installed base benefits.
Completely synergize resource taxing relationships via premier niche markets. Professionally cultivate one-to-one customer service with robust ideas. Dynamically innovate resource-leveling customer service for state of the art customer service.
Amwerk vision
Phosfluorescently engage worldwide methodologies with web-enabled technology. Interactively coordinate proactive e-commerce via process-centric “outside the box” thinking. Completely pursue scalable customer service through sustainable potentialities.
Collaboratively administrate turnkey channels whereas virtual e-tailers. Objectively seize scalable metrics whereas proactive e-services. Seamlessly empower fully researched growth strategies and interoperable internal or “organic” sources.
Credibly innovate granular internal or “organic” sources whereas high standards in web-readiness. Energistically scale future-proof core competencies vis-a-vis impactful experiences.
Interactively procrastinate high-payoff content without backward-compatible data. Quickly cultivate optimal processes and tactical architectures. Completely iterate covalent strategic theme areas via accurate e-markets, media information without cross-media value.
Give us a call
414-214-0362
Email us
info@amwerk.com
Cleveland
3644 Rocky River Drive, Ohio 44111, United States
Michigan
1099 Springland Ave, Indiana 46360, United States
Founder and owner
Peter Trebuchet
- Career & Experience
- Recognitions & Awards
Progressively maintain extensive infomediaries via extensible niches. Dramatically disseminate standardized metrics after resource-leveling processes. Objectively pursue diverse catalysts for change for interoperable meta-services.
Proactively fabricate one-to-one materials via effective e-business. Completely synergize scalable e-commerce rather than high standards in e-services. Assertively iterate resource maximizing products after leading-edge intellectual capital.
More from AmwerkAmwerk services
Intrinsically incubate intuitive opportunities and real-time potentialities. Appropriately communicate one-to-one technology after plug-and-play networks.
Our leadership
Pravin Kumar
He has a double doctorate in Computational Biology & Chemistry and Protein engineering. With 18 years of industrial experience working on different projects related to target deconvolution studies and enzyme engineering studies, his main interest is to develop technologies that make enzyme engineering and protein optimization, easy & faster to accelerate economic growth and opportunity.
Gladstone Sigamani
He holds an M.Tech in Machine Learning and has been in the Software Industry for 10 years. He has a strong technical expertise in Artificial Intelligence and different programming languages. He is highly fascinated by the way proteins and enzymes work and hence currently is pursuing research in understanding the proteins with AI. He implements AI to tap crucial information about how a single mutation can change the stereospecificity of a protein.
Roopa Lalitha
She is a Computational Biologist and has a Ph.D. in Computational Biology. She comes with 14 years of experience in Computational chemistry/ Biology, and also is pursuing her second Ph.D. in Protein Engineering. She has extensive research expertise and has several international publications.
Our History
2018
August 2018
Kcat’s Inception in Paris in EuroSciCon
Oct 4th, 2018
Started Office in Co-working space – 3 Founders, just 2 Interns, No Employees, No Projects
2019
March 2019
Our dedicated Computational facility in Cox Town from co-working space
Sep 2019
Kcat’s 7D Grid Technology was recognized as “Novel Tools in Enzyme Engineering” Enzyme Engg Consortium.
Oct 2019
Pfizer visits Kcat’s Office in Cox Town
2020
March 2020
Kcat’s Molecular Biology Facility in Bangalore Bioinnovation Center
July 2020
Kcat received the Prestigious BIRAC BIG Grant from the Dept. of Biotechnology, India.
August 2020
Kcat receives 2 back-to-back UKRI Grants
2021
Jan 2021
Building of Enzyme Libraries – Engineered Enzyme Kits for diverse applications – Own Products
July 2021
Hon’ble Finance Ministers Smt. Nirmala Seetharaman’s Visit
August 2021
Established Fermentation Capabilities & gram scale protein production.
Sep 2021
Kcat releases 7 products – Engineered Enzyme Kits for diverse biocatalysis applications
Oct 2021
Supplied the Engineered Enzyme Kits to domestic and International Customers in Germany & UK
Oct 2021
Kcat received the Prestigious National Institute of Health (NIH) – USA
Nov 2021
Signed Contracts for Enzyme Manufacturing & Continuous Supply of Enzymes
Dec 2021
Established manufacturing of Engineered Lipase through contract manufacturing mode at Kilogram scale.
Dec 2021
Got some promising results in engineering flourinase – the toughest Enzyme Engineering Problem
2022
Jan 2022
KCAT Filed its First International Patent – 7D Grid & CRISPR Cas Technology
Feb 2022
KCAT Published its research work in top journals in ACS Catalysis, Catalysis Today, Journal of Biological Chemistry
Mar 2022
Automated Lab for Enzyme Screening
April 2022
Kcat manuscript, “Structure dynamics and molecular inhibition of the Staphylococcus aureus m1A22-tRNA methyltransferase TrmK” has been selected as one of JBC’s “Editors Picks”.
May 2022
Kcat is once again recognized by the “Enzyme Engineering Consortium”.
Texas Dallas/Fort Worth
2023
March 2023
Kcat Enzymatic has successfully secured its first investment from Ideaspring Capital, marking a significant milestone in our journey towards creating a sustainable future for a more resilient tomorrow.
April 2023
We are extremely delighted to see you all at CPHI North America 2023. Come visit us at our booth #135.
Feel free to get in touch with us to discover how our state-of-the-art AI-powered technology can revolutionize your manufacturing process with novel biocatalytic routes. 
January 2024
We are extremely delighted to announce our latest research publication on “Modulation of Glucose 6 Phosphatase System by Chlorogenic Acids: A New Frontier in Diabetes Treatment.”
#kcat #newpublication #translocase
August 2024
We’re excited to announce our latest publication in Nature Scientific Reports on proteins with double active sites, which could revolutionize enzyme design strategies. “Computational studies on the catalytic potential of the double active site for enzyme engineering”
July 2024
We are extremely delighted to announce the granting of our patent “Insilico Guided CRISPR-Cas Driven Enzyme Engineering Framework.”
𝑨 𝑵𝒆𝒘 𝑷𝒓𝒐𝒕𝒆𝒊𝒏 𝑬𝒏𝒈𝒊𝒏𝒆𝒆𝒓𝒊𝒏𝒈 𝑻𝒐𝒐𝒍: 𝑬𝒏𝒈𝒊𝒏𝒆𝒆𝒓𝒆𝒅 𝑪𝑹𝑰𝑺𝑷𝑹-𝑪𝒂𝒔 𝑮𝒖𝒊𝒅𝒆𝒅 𝒃𝒚 𝑨𝑰 𝑫𝒆𝒔𝒊𝒈𝒏 𝒇𝒐𝒓 𝒆𝒏𝒈𝒊𝒏𝒆𝒆𝒓𝒊𝒏𝒈 𝒆𝒏𝒛𝒚𝒎𝒆𝒔.
