Kcat Enzymatic brings Enzyme Engineering & Biocatalysis Revolution by using upfront in-silico in-house developed methods and algorithms using 7D Grid Technology for enzyme engineering (Patent No: 201841047021). In this line, a new and advanced way of enzyme engineering methods were developed to use enzymes in industrial processes. Our multiscale methods and technologies gives custom engineered...
The Coronavirus outbreak came to light on December 31, 2019 when China informed the World Health Organization. The growing COVID-19 global health crisis led us to contribute in scientific community. Kcat has contributed in identifying (Patent No: 202041038649, 08th Sep-20) antiviral compounds that can modulate the Cysteine protease Mpro and Spike protein of covid-19.
A plant-derived composition of active ingredients of certain plant extracts is provided to treat the affections of the Human Upper and Lower Respiratory Tract. The invention applies to healing and curative effects of certain active ingredients in the extracts of plants such as Wilbrandia ebracteate, Plumbago zeylanica, Azadirachta indica, Juglans nigra, Eucalyptus globulus, Mentha piperita,...
Enzyme engineering is a highly sophisticated and time intensive process. In order to complement in-vitro studies and streamline the screening process for the selection of enzyme variants, in-silico analyses provide a suitable platform, as various steps can be efficiently automated with little to no burden on time and resources. In this study, we provide a...
7D Grid Technology uses Quantum Mechanic probes to “capture information across the enzymatic reaction and across the enzyme-substrate system”. This information is used by AI methods, Convolutional Neural Networks, and Support Vector Machines, to design enzymes and derive focused libraries. Based on the projects done in the last 2.5 years, we can say that promiscuous...
The indirect flight muscles (IFMs) of Drosophila melanogaster provide a good model for understanding muscle development and function in vivo. We show that two missense mutations in the rod region of the myosin heavy-chain gene, Mhc, give rise to IFM defects and abnormal myofibrils. Molecular dynamics simulations suggest that these mutations may produce localized rod...
